Lili Niu
Short Profile
I joined Simon’s lab in December 2020 as a joint Postdoc with the Clinical Proteomics group led by Prof. Matthias Mann. Before that, I finished my PhD project in the Mann Group working on biomarker discovery for liver diseae using mass spectrometry-based proteomics.
Main Postdoc Project
My main Postdoc project is developing and applying proteogenomics pipeline to understand human proteome variation. For this, I incorporate individual specific genetic information to create customized protein sequence database. This allows us to identify variant peptides that are typically not covered in the reference human proteome database, examine the impact of variant peptides on protein quantification and their role in disease development. Another main focus of my Postdoc project is population-based plasma proteome profiling. An ongoing project is the plasma proteomics analysis of 2000 children and adolescents, aiming to undetstand age- and sex-dependent plasma proteome changes, as well as to identify biomarkers for childhood obesity and related metabolic phenotypes. This project is in collaboration with Prof. Torben Hansen at CBMR and Prof. Jens-Christian Holm at the Children’s Obesity Clinic in Holbaek, Denmark
Short CV
- 12/2020–present: Postdoc researcher Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark.
- 09/2016–11/2020: PhD candidate at Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark; enrolled in the Copenhagen Bioscience PhD Program,
- 06/2016–08/2016: Research assistant at Dept. Proteomcis and Signal Transduction, Max Planck Institute of Biochemistry in Martinsried, Germany
- 09/2012–06/2015: Master student at HuaZhong University of Science and Technology, co-trained at Institute of Biophysics, Chinese Academy of Sciences